Aptamer 学术简报 — infectious_disease — 2026-07-12

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 infectious_disease：近 14 天 7 篇命中（aptamer 池 245 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [10.0] Quo Vadis, Electrochemical DNA Biosensor? Lessons from Three Decades of SNP Sensing.

Electrochemical DNA biosensors have been studied for over three decades, producing thousands of publications and a sophisticated engineering toolkit. However, a broad clinical adoption remains limited. The COVID-19 pandemic served as a stress test-global demand, unprecedented funding, accelerated regulatory pathways, and a clearly defined genomi...

#2 [9.6] Aptamer-powered surveillance of SARS-CoV-3.

Rapid detection of emerging coronaviruses is critical for preparedness. The S2A2C1 aptamer broadly recognizes Beta-coronavirus S2 domains but not influenza proteins. A sandwich aptamer assay achieved ∼0.51 pM detection limits and functions in serum, enabling a sensitive, adaptable platform for universal coronavirus detection and real-time survei...

#3 [8.7] SELEX to Clinic: Evolution, Innovations and Applications of Aptamers in Precision Medicine

Aptamers are short, single-stranded DNA or RNA oligonucleotides selected in vitro via SELEX (Systematic Evolution of Ligands by Exponential Enrichment) that fold into defined 3-D structures and bind cognate targets with antibody-like affinity yet superior versatility. Thirty-five years after their simultaneous disclosure by Ellington & Szostak a...

#4 [8.7] SELEX to Clinic: Evolution, Innovations and Applications of Aptamers in Precision Medicine

Aptamers are short, single-stranded DNA or RNA oligonucleotides selected in vitro via SELEX (Systematic Evolution of Ligands by Exponential Enrichment) that fold into defined 3-D structures and bind cognate targets with antibody-like affinity yet superior versatility. Thirty-five years after their simultaneous disclosure by Ellington & Szostak a...

#5 [8.3] History and future of RNA medicines.

RNA therapeutics are a versatile class of medicines that exploit different types of RNA molecules to prevent or treat a wide spectrum of diseases. Compared with traditional small-molecule drugs, protein drugs, or gene therapies, these therapies offer notable advantages, including faster, less expensive development, and simplified manufacturing. ...

#6 [6.3] Recombinant Taq DNA polymerase.

The sudden COVID-19 pandemic highlights the importance of diagnostic assays in health security readiness. One persistent difficulty is the rapid molecular detection of pathogenic microorganisms and viruses. Taq DNA polymerase remains an essential component for COVID-19 molecular detection. Taq DNA polymerase exhibits a high level of thermostabil...

#7 [5.7] Polyaniline metal dichalcogenide-based amplified aptasensor for SARS-CoV-2 spike glycoprotein detection in wastewater

The significance of nanocomposites (NCs) in the academic and industrial fields has been of great focus due to the combination of various qualities of different nanomaterials, with the aim of achieving controlled properties. In this work, the aptasensor fabrication consists of a SARS-CoV-2 spike glycoprotein specific thiolated aptamer (HS-Apt) im...

Methodology