Aptamer 学术简报 — cancer — 2026-09-04

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 cancer：近 14 天 50 篇命中（aptamer 池 229 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [18.1] Specific detection against PSA by using emission wavelength of carbon dots modulates TiO(2)/In(2)S(3)-based photoelectrochemical aptasensor.

Sensitive and precise detection of prostate-specific antigen (PSA) is essential for the early diagnosis and monitoring of prostate cancer. However, conventional detection methods often suffer from limited sensitivity, poor selectivity, highlighting the need for advanced sensing platforms. Photoelectrochemical (PEC) biosensing achieve for PSA acc...

#2 [13.8] Aptamer-mediated portable SERS sensor based on bimetallic magnetic nanotubes for internal standard-calibrated detection of multi-target disease markers.

Accurate early screening for hepatocellular carcinoma (HCC) requires multi-target detection methods with high sensitivity and strong anti-interference capability. In this study, we developed an aptamer-mediated SERS sensing method based on bimetallic magnetic nanotubes for the simultaneous detection of HCC markers alpha-fetoprotein (AFP) and Gol...

#3 [13.0] Catalytic BiFeO3/g-C3N4 Heterojunction Nanosheets Coupled with DNAzyme/Low-Leakage Sequential DNA Circuit for Ultrasensitive Electrochemical Aptamer-Based Detection of Colorectal Cancer Exosomes.

Tumor-derived exosomes are promising circulating biomarkers for early colorectal cancer (CRC) diagnosis, yet their low abundance and the complexity of biological fluids demand sensing strategies with both stringent specificity and amplified signal output. Here, we report an ultrasensitive electrochemical aptasensor for SW620 cell-derived exosome...

#4 [12.6] Conducting Polymer–Nanomaterial Hybrids for Cancer Diagnostics

Cancer continues to pose a major global burden because of the high incidence and mortality, underscoring the urgent need for innovative and highly sensitive diagnostic technologies. Conducting polymer–nanomaterial (CP–NM) hybrid biosensors have become promising platforms for cancer biomarker detection, integrating the redox-active and biocompati...

#5 [12.5] Oxygen vacancies-induced dual-interface modulation for TiO(2)/BiOI-based photoelectrochemical biosensor of urinary cancer markers.

Non-invasive urine-based cancer biomarker detection holds significant clinical value in cancer screening, treatment efficacy monitoring, recurrence warning, and auxiliary diagnosis. To address the issues of poor sensitivity and selectivity in photoelectrochemical (PEC) biosensing for the detection of cancer biomarkers in urine, oxygen vacancies ...

#6 [12.0] Flexible 3D-Printed Polydimethylsiloxane Microdevice with a Ternary Heterojunction-Engineered Photoanode for Sensitive Photoelectrochemical Detection of Tumor Necrosis Factor-α in Sweat.

The detection of low-abundance biomarkers in sweat with high sensitivity is essential for wearable health monitoring applications. However, the performance of conventional photoelectrochemical (PEC) sensors is constrained by their rigid substrates, inefficient charge separation, and limited miniaturization capability. This study develops a flexi...

#7 [11.8] Computational Design of RNA Aptamers Targeting Oncogenic miR-10b Using T-SELEX and Molecular Dynamics-Based Stability Metrics

Abstract Aptamers are versatile single-stranded nucleic acids with high specificity and stability, making them ideal for targeting challenging biomolecules. Their structural flexibility enables selective recognition of nonprotein targets such as microRNAs (miRNAs). Among these, miR-10b plays a pivotal role in cancer progression and metastasis th...

#8 [11.7] A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

Precision control over nucleic acid delivery remains a critical challenge in cancer therapy, particularly for siRNA-based gene silencing, where off-target effects limit clinical translation. Herein, we report a programmably engineered DNA nanocircuit with cascaded dual-AND logic gates, which enables the development of a spatiotemporally controll...

#9 [11.6] Application of aptamer nucleic acid test strips in the detection of tumor markers for colorectal cancer.

At present, the detection methods of tumor markers rely on ELISA, gene sequencing, and other technologies. However, these methods require specialized equipment and technical personnel, and the low concentrations of early tumor markers limit their sensitivity. This study developed a method for detecting colorectal cancer tumour markers. It uses a...

#10 [11.5] Aptamer-functionalized terahertz metasensor for sensitive and specific determination of alpha-fetoprotein.

Alpha-fetoprotein (AFP) is a key serum biomarker for the early diagnosis of hepatocellular carcinoma (HCC). In this study, a dual-band terahertz (THz) metasurface sensor (metasensor) was developed and functionalized with computationally selected aptamers for sensitive and specific detection of AFP. A 1000-sequence ssDNA library was screened usin...

Methodology