Aptamer 学术简报 — biosensor — 2026-09-01

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 132 篇命中（aptamer 池 199 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [14.8] Aptamer-mediated portable SERS sensor based on bimetallic magnetic nanotubes for internal standard-calibrated detection of multi-target disease markers.

Accurate early screening for hepatocellular carcinoma (HCC) requires multi-target detection methods with high sensitivity and strong anti-interference capability. In this study, we developed an aptamer-mediated SERS sensing method based on bimetallic magnetic nanotubes for the simultaneous detection of HCC markers alpha-fetoprotein (AFP) and Gol...

#2 [14.8] Double-target responsive FRET sensor based on DNA tetrahedron for robust detection of liver fibrosis-related mRNAs in activated hepatic stellate cells.

Early diagnosis and graded evaluation of liver fibrosis remained challenging due to the limited sensitivity and accuracy of current noninvasive diagnostic tools. The imaging strategy of intracellular disease-related biomarker based on DNA nanoparticles had been used for accurate diagnosis and prognosis studies. However, their sensitivity and acc...

#3 [14.8] A novel triple-mode sensor utilizing trimetallic derived fluorescent carbon dots nanozyme for tetracycline determination.

Tetracycline (TC) is notoriously resistant to degradation in natural environments, which contributes to its prolonged persistence and widespread contamination. Improper or excessive use of TC can lead to multifaceted hazards. In this study, we developed a trimetallic-doped carbon dots (Fe,Cu,Ce-CDs)-based composite that exhibits distinct fluores...

#4 [14.8] Self-powered photoelectrochemical aptasensor based on CHA-triggered G-quadruplex/hemin cascade for homogeneous detection of ochratoxin A in a separated-coupling electrolysis system.

To address the challenge of electroactive interferences derived from complex food matrices during homogeneous photoelectrochemical (PEC) biosensing, a "separated-coupling" electrolysis platform was rationally engineered for the ultrasensitive detection of ochratoxin A (OTA). Based on the analysis of the conduction band of the α-Fe2O3 photoanode ...

#5 [13.8] Rational design of Cr(VI) aptamer guided by revealed cation-mediated binding mechanism and construction of a label-free fluorescent aptasensor.

Aptasensors are widely recognized as practical and rapid detection tools for heavy metal pollution due to their high specificity and sensitivity. However, screening aptamers for small molecules (including ions) is significantly challenging. To date, only two Cr(VI) aptamers have been reported, which cannot meet the demand of aptasensor developme...

#6 [13.8] From rational engineering of a broad-spectrum aptamer to multi-residue screening: A fluorescent aptasensor for multiplexed sulfonamides.

The increasing prevalence of multiple antibiotic residues in animal-derived foods presents significant challenges for monitoring efforts. Broad-spectrum aptamers offer great promise for enabling multiplex detection of various antibiotic residues. However, aptamers directly screened for this purpose often exhibit low affinity and poor stability, ...

#7 [13.8] Nanomaterial-enabled CRISPR-Cas biosensing for non-nucleic acid targets: Strategies, mechanisms, and applications.

Nanomaterial-assisted CRISPR-Cas biosensing has transcended nucleic acid detection, emerging as a prominent paradigm for the ultrasensitive analysis of non-nucleic acid targets. This review systematically elucidates recent advances by proposing a novel three-dimensional framework encompassing transduction efficiency, signal output, and applicati...

#8 [13.8] A bimetallic metal-organic framework-based aptasensor for dual-mode colorimetric and fluorescent detection of Fumonisin B(1).

Fumonisin B1 (FB1) is a secondary metabolite produced by Fusarium species and is considered one of the most dangerous mycotoxins. It is widely present in maize and other agricultural commodities, posing severe threats to human health and animal husbandry. Consequently, the development of a convenient and rapid detection method is of paramount im...

#9 [13.8] Electrochemical biosensor for ultrasensitive thrombin detection based on aptamer-modulated transcriptional inhibition of cell-free synthetic biology.

In this study, a novel strategy integrating aptamer-gated cell-free synthetic biology with electrochemical analysis has been developed for thrombin detection (using thrombin as a model target). A DNA template embedded with a target-specific aptamer is designed as a "molecular switch". Target binding induces a conformational change in the aptamer...

#10 [13.8] Au-Ag NFs@Pt NCs nanozymes-driven aptasensor for sensitive visual detection of aflatoxin B1 in peanut.

Nanozyme-based aptasensors still face challenges, including low catalytic activity and inverse signal correlation, which hinder their advancement in the field of food safety. To address these issues, this study developed a novel nanozyme-based colorimetric aptasensor for the high-performance detection of AFB1. Initially, a gold-silver alloy nano...

Methodology