Aptamer 学术简报 — biosensor — 2026-07-05

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 150 篇命中（aptamer 池 233 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [24.0] Magnetically induced aggregation-assisted mesoporous polydopamine/single-atom nanozyme platform for dual-channel detection and two-stage synergistic eradication of pathogens.

Contamination with foodborne pathogenic bacteria poses a severe threat to public health, necessitating the integration of detection with source sterilization technologies. Herein, we developed an integrated nanoplatform by combining an aptamer-modified mesoporous polydopamine/palladium single-atom carbon dot composite probe (MPDA/Pd SA@DA-CDs/Ap...

#2 [24.0] High affinity and selective DNA aptamers for the detection of tobramycin in eye drops.

Tobramycin is a frontline aminoglycoside antibiotic with a narrow therapeutic window. Here, we report the selection of high-affinity DNA aptamers using a library-immobilization based SELEX strategy. The lead aptamer, TOB-2, binds tobramycin with a dissociation constant of 420 nM as determined by isothermal titration calorimetry, while exhibiting...

#3 [20.6] Microscale thermophoresis sensor for homogeneous and one-step protein detection based on dual aptamers binding induced DNA switch.

Rapid and sensitive detection of proteins is in great demand in disease diagnostics, drug discovery, basic research, and other biomedical applications. The emerging microscale thermophoresis (MST) technique, which enables to monitor fluorescence responses of fluorescent molecules under heating in real time, provides an attractive avenue for sens...

#4 [20.6] Multiplexed biosensing: A review of surface plasmon resonance platforms for biomarker analysis.

Surface plasmon resonance (SPR) has emerged as an important optical technology for the real-time, label-free analysis of biomolecular interactions. While its utility in detecting single analytes is well-established, the growing complexity of disease diagnostics demands tools capable of simultaneous multi-analyte detection. Many complex diseases,...

#5 [20.2] AI-driven Cu/Mn-CeO(2) nanozyme-functionalized paper-based biosensor for quantitative monitoring of alternariol in food.

The lack of rapid, user-friendly methods for alternariol (AOH), a prevalent emerging mycotoxin, presents a considerable analytical challenge. This work introduces an integrated sensing strategy advancing from classical homogeneous liquid-phase detection to a portable AI-enhanced paper-based biosensor. The system employed a Cu/Mn-CeO2 nanozyme as...

#6 [16.9] Ultrasensitive, Real-Time Molecular Sensing in Unprocessed Whole Blood Using Surface-Enhanced Raman Scattering Combined with Glycocalyx-Mimicking Structures.

Rapid, real-time, and ultrasensitive molecular sensing in unprocessed whole blood remains a major challenge due to biofouling, narrow dynamic ranges, and the need for rapid equilibration. We report a biomimetic surface-enhanced Raman scattering (SERS) platform that integrates structure-switching aptamers with a self-assembling, lubricin (proteog...

#7 [16.8] Next-generation electrochemical aptasensors for thrombin detection: the rise of aptamer-MOF architectures.

Thrombin is a crucial regulatory enzyme in the blood coagulation cascade that significantly influences cancer metastasis, cardiovascular disease, inflammation, and immunological regulation. Because of its dynamic, concentration-dependent activity, thrombin has emerged as a potential biomarker for the early diagnosis of a wide range of pathologic...

#8 [15.8] A photocurrent polarity switching photoelectrochemical aptasensor based on Er-MOF nanosheets and methylene blue for high-performance determination of CA15-3.

BACKGROUND: Photoelectrochemical (PEC) biosensors have attracted increasing interest for tumor biomarker detection due to their intrinsic advantages. However, conventional PEC sensing strategies are typically based on unidirectional "signal-on" or "signal-off" modes, which are vulnerable to matrix interferences in complex biological samples and ...

#9 [14.5] Porous Hydrogel-Mediated One-Step Selection of Mannoprotein-Targeted Aptamers for Early Diagnosis of Invasive Saccharomyces cerevisiae Infections.

Invasive fungal infections, particularly those caused by Saccharomyces cerevisiae, have emerged as a significant public health threat. Accurate and timely recognition of S. cerevisiae is essential for effective diagnosis and treatment. This study introduces a micro- and nanoscale-enabled diagnostic strategy that integrates porous hydrogel-mediat...

#10 [14.0] Smartphone-Enabled Point-of-Care Biosensing Platform With Self-Calibration for Rapid Matrix-Resistant Detection of Multiple AMI Biomarkers in Whole Blood.

Acute myocardial infarction (AMI) requires rapid diagnosis beyond conventional methods, which suffer from biological interference and complexity, limiting point-of-care (POC) application. To tackle these issues, we have devised an anthraquinone (AQ)-calibrated sensor unit coupled with smartphone-based analysis for universal detection of AMI biom...

Methodology