Aptamer 学术简报 — 2026-09-08

自动生成 by RBTX Aptamer Tracker v0.1。 近 14 天入库 231 篇 aptamer-related papers。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [24.3] Self-powered photoelectrochemical aptasensor based on CHA-triggered G-quadruplex/hemin cascade for homogeneous detection of ochratoxin A in a separated-coupling electrolysis system.

To address the challenge of electroactive interferences derived from complex food matrices during homogeneous photoelectrochemical (PEC) biosensing, a "separated-coupling" electrolysis platform was rationally engineered for the ultrasensitive detection of ochratoxin A (OTA). Based on the analysis of the conduction band of the α-Fe2O3 photoanode ...

#2 [22.5] A novel triple-mode sensor utilizing trimetallic derived fluorescent carbon dots nanozyme for tetracycline determination.

Tetracycline (TC) is notoriously resistant to degradation in natural environments, which contributes to its prolonged persistence and widespread contamination. Improper or excessive use of TC can lead to multifaceted hazards. In this study, we developed a trimetallic-doped carbon dots (Fe,Cu,Ce-CDs)-based composite that exhibits distinct fluores...

#3 [19.9] Electrochemically covalent lock stabilizes aptamer conformation and strengthens its sensing performance for PFOA.

PER: and polyfluoroalkyl substances (PFAS) are widely detected emerging pollutants, yet their accurate identification in complex water remains a major challenge. Herein, we developed an innovative aptamer (Apt) -based electrochemical molecularly imprinted polymer (MIP) sensor for high-sensitivity detection of perfluorooctanoic acid (PFOA) in com...

#4 [17.8] From rational engineering of a broad-spectrum aptamer to multi-residue screening: A fluorescent aptasensor for multiplexed sulfonamides.

The increasing prevalence of multiple antibiotic residues in animal-derived foods presents significant challenges for monitoring efforts. Broad-spectrum aptamers offer great promise for enabling multiplex detection of various antibiotic residues. However, aptamers directly screened for this purpose often exhibit low affinity and poor stability, ...

#5 [17.8] Nanomaterial-enabled CRISPR-Cas biosensing for non-nucleic acid targets: Strategies, mechanisms, and applications.

Nanomaterial-assisted CRISPR-Cas biosensing has transcended nucleic acid detection, emerging as a prominent paradigm for the ultrasensitive analysis of non-nucleic acid targets. This review systematically elucidates recent advances by proposing a novel three-dimensional framework encompassing transduction efficiency, signal output, and applicati...

#6 [17.8] A bimetallic metal-organic framework-based aptasensor for dual-mode colorimetric and fluorescent detection of Fumonisin B(1).

Fumonisin B1 (FB1) is a secondary metabolite produced by Fusarium species and is considered one of the most dangerous mycotoxins. It is widely present in maize and other agricultural commodities, posing severe threats to human health and animal husbandry. Consequently, the development of a convenient and rapid detection method is of paramount im...

#7 [15.2] SOLiD-MaP: A Photoproximity Labeling Platform for Small Molecule Binding Site Mapping on RNA.

RNA-targeting small molecules are emerging as promising therapeutic modalities, but their development requires methods that define binding sites and evaluate RNA target selectivity. Existing approaches for detecting ligand-RNA interactions have provided powerful foundations, yet many rely on direct cross-linking or covalent-capture chemistries w...

#8 [14.5] Selection and validation of novel DNA aptamer panel co-specific to Plasmodium falciparum and Plasmodium ovale lactate dehydrogenase.

Malaria remains a major global health concern. The development of point-of-care diagnostic aptasensors could improve malaria detection, patient management, and eradication efforts. We selected and validated single-stranded DNA aptamers against Plasmodium falciparum lactate dehydrogenase (Pf-LDH), using systematic evolution of ligands by exponent...

#9 [14.5] Mammalian therapeutic riboswitches: Engineering and custom ligands.

Regulation with riboswitches, which induce or repress gene expression in response to a ligand, is moving from proof-of-concept studies to robust clinical-grade gene therapies. These initial stages in RNA-based precision medicine will soon benefit from the next generation of riboswitches, whose engineering results from the combination of deep lea...

#10 [14.5] Leveraging the unique properties of RNA aptamers to quantify the fraction of receptors occupied by ligands.

Methodology