Aptamer 学术简报 — 2026-09-02

自动生成 by RBTX Aptamer Tracker v0.1。 近 14 天入库 193 篇 aptamer-related papers。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [33.5] Self-powered photoelectrochemical aptasensor based on CHA-triggered G-quadruplex/hemin cascade for homogeneous detection of ochratoxin A in a separated-coupling electrolysis system.

To address the challenge of electroactive interferences derived from complex food matrices during homogeneous photoelectrochemical (PEC) biosensing, a "separated-coupling" electrolysis platform was rationally engineered for the ultrasensitive detection of ochratoxin A (OTA). Based on the analysis of the conduction band of the α-Fe2O3 photoanode ...

#2 [31.6] A novel triple-mode sensor utilizing trimetallic derived fluorescent carbon dots nanozyme for tetracycline determination.

Tetracycline (TC) is notoriously resistant to degradation in natural environments, which contributes to its prolonged persistence and widespread contamination. Improper or excessive use of TC can lead to multifaceted hazards. In this study, we developed a trimetallic-doped carbon dots (Fe,Cu,Ce-CDs)-based composite that exhibits distinct fluores...

#3 [28.9] Electrochemically covalent lock stabilizes aptamer conformation and strengthens its sensing performance for PFOA.

PER: and polyfluoroalkyl substances (PFAS) are widely detected emerging pollutants, yet their accurate identification in complex water remains a major challenge. Herein, we developed an innovative aptamer (Apt) -based electrochemical molecularly imprinted polymer (MIP) sensor for high-sensitivity detection of perfluorooctanoic acid (PFOA) in com...

#4 [26.6] From rational engineering of a broad-spectrum aptamer to multi-residue screening: A fluorescent aptasensor for multiplexed sulfonamides.

The increasing prevalence of multiple antibiotic residues in animal-derived foods presents significant challenges for monitoring efforts. Broad-spectrum aptamers offer great promise for enabling multiplex detection of various antibiotic residues. However, aptamers directly screened for this purpose often exhibit low affinity and poor stability, ...

#5 [26.6] Nanomaterial-enabled CRISPR-Cas biosensing for non-nucleic acid targets: Strategies, mechanisms, and applications.

Nanomaterial-assisted CRISPR-Cas biosensing has transcended nucleic acid detection, emerging as a prominent paradigm for the ultrasensitive analysis of non-nucleic acid targets. This review systematically elucidates recent advances by proposing a novel three-dimensional framework encompassing transduction efficiency, signal output, and applicati...

#6 [26.6] A bimetallic metal-organic framework-based aptasensor for dual-mode colorimetric and fluorescent detection of Fumonisin B(1).

Fumonisin B1 (FB1) is a secondary metabolite produced by Fusarium species and is considered one of the most dangerous mycotoxins. It is widely present in maize and other agricultural commodities, posing severe threats to human health and animal husbandry. Consequently, the development of a convenient and rapid detection method is of paramount im...

#7 [22.7] Specific detection against PSA by using emission wavelength of carbon dots modulates TiO(2)/In(2)S(3)-based photoelectrochemical aptasensor.

Sensitive and precise detection of prostate-specific antigen (PSA) is essential for the early diagnosis and monitoring of prostate cancer. However, conventional detection methods often suffer from limited sensitivity, poor selectivity, highlighting the need for advanced sensing platforms. Photoelectrochemical (PEC) biosensing achieve for PSA acc...

#8 [22.7] Selection and characterization of biofilm-degrading aptamers against Vibrio anguillarum, Vibrio alginolyticus, and Vibrio harveyi and their target protein interaction analysis.

Vibrio is an important pathogenic bacterium, and its pathogenicity and drug resistance are greatly enhanced by its biofilm-forming ability, posing serious threats to food safety and public health. The present study employed Inhibition-Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technology to independently screen aptamers th...

#9 [15.2] Co-Assembled Mirror-Image DNA Nanostructure for Effective Alleviation of Acute Kidney Injury.

The high demand for acute kidney injury (AKI) therapy calls for the development of new therapeutics for renal management. Oxidative stress, coupled with excessive inflammation, is the main pathological mechanism for AKI. Specifically, complement component 5a (C5a) exacerbates the vicious cycle between oxidative stress and inflammatory responses....

#10 [14.9] A Receptor-Mediated Endolysosomal Recycling Chimera Enables Catalytic TNF-α Degradation for Sustained Treatment of Mucosal Inflammation.

Mucosal inflammatory disorders such as dry eye disease (DED) and inflammatory bowel disease (IBD), driven by TNF-α-mediated immune-epithelial crosstalk, remain therapeutically challenging. Conventional inhibitors often suffer from poor mucosal permeability and transient efficacy with 1:1 binding. Although extracellular protein degradation (eTPD)...

Methodology